Next-Generation DNA-Seq

Next-Generation DNA-Seq

DNA sequencing technology has long been one of the most commonly used technical tools in molecular biology research and has greatly advanced the field. The next-generation DNA sequencing technology has brought research related to genomics and molecular biology to a new level. Next-generation DNA sequencing has the advantages of high throughput, high efficiency, and low cost compared to generation sequencing, enabling rapid sequencing of hundreds to millions of DNA molecules from hundreds to thousands of samples simultaneously. At CD Genomics, we provide you with comprehensive next-generation DNA sequencing services based on our advanced sequencing platform.

Next-Generation DNA-Seq Services

• ChIP-Seq: Chromatin immunoprecipitation (ChIP) sequencing is performed to obtain protein-DNA binding sites.
• Hi-C Seq: A method to analyze the three-dimensional spatial structure of chromatin using high-throughput sequencing technology with the whole nucleus as the target.
• ATAC-Seq: Genome-wide transposase-capable and DNA sequencing is a new epigenetic technique for exploring chromatin conformation.
• Micro-C Seq: Use of micrococcal nuclease (MNase) to obtain chromosome interaction maps with resolution up to the nucleosome level.
• Amplicon Sequencing: A method for deep sequencing of amplicon fragments, capable of detecting very low levels and frequencies of variation.
• Whole Genome Sequencing: Sequencing the entire genome of an organism, enabling the determination of the genome sequence of previously unsequenced species.
• Whole Exome Sequencing: Using sequence capture technology to capture and enrich DNA from exonic regions of the entire genome for high-throughput sequencing, typically used in humans to discover rare or common variants associated with disease or phenotype.
• Targeted Sequencing: Targeted sequencing is a technique in which a genomic region of interest is amplified or captured, then enriched and sequenced.
• Whole Genome Resequencing: Sequencing the genomes of different individuals or species with known genome sequences to perform differential analysis of individuals or populations.
• Metagenomic Sequencing: To explore the functional activity, inter-collaborative relationships, and relationships between microbial communities and their environment to uncover potential biological significance.
• Microbiome Sequencing: Analysis of genes such as bacterial (16S rDNA), fungal (18S/ITS), and functional genes by PCR amplification of specific lengths and sequencing of the amplification products.
• TCR Beta Sequencing: Sequencing analysis on all regions of the TCR beta chain including CDR1, CDR2, and CDR3 to facilitate immuno-oncology studies.
• BCR Sequencing: For detecting various immune-related diseases, genetic mutation-induced BCR gene rearrangements, and changes in abundance.

Our Sequencing Platforms

• NextSeq 500 NGS System
• Two MiSeq NGS Systems
• NovaSeq 6000 NGS System, etc.

Applications

• Species identification.
• Analysis of protein-DNA interactions.
• Analysis of the three-dimensional spatial structure of chromatin.
• Exploration of the association between genes and diseases.
• Analysis of genetic variability and detection of variation information.

Our Workflow

CD Genomics provides you with customized next-generation DNA sequencing solutions through our state-of-the-art sequencing platform. We provide a one-stop service from DNA extraction to data analysis that can advance your genomics and molecular biology-related research. If you need related technical support, please feel free to contact us.

For research use only, not for any clinical use.